欧美色欧美亚洲高清在线视频,亚洲资源AV无码日韩AV无码,亚洲中文字幕av无码一区

鄭重說明:

您值得信賴的中藥成分及標準合作伙伴滿足您研發和工業化需求

產品關鍵詞：香草酸-4-β-D-葡萄糖苷 6-甲氧基山奈酚茯苓新酸B 去甲異波爾定

guanyuwomen關于德思特

聯系方式

服務熱線：

028-8500-3950

公司傳真：	028-85589956
公司郵箱：	sales@tcmlmt.com
公司網址：	hamilton.org.cn
公司地址：	四川省成都市溫江區海科路西段128號5棟

發表文獻展示

當前位置:首頁關于德思特 > 發表文獻展示 >

Molecules-23 July 2019 半齒澤蘭素

時間：2020-09-03 瀏覽次數：分享到：

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS
期刊名：Molecules
文獻編號：DOI 10.3390/molecules24142658
文獻地址：https://www.mdpi.com/1420-3049/24/14/2658
發表日期：23 July 2019

Abstract
Eupatorin is the major bioactive component of Java tea (Orthosiphon stamineus), exhibiting strong anticancer and anti-inflammatory activities. However, no research on the metabolism of eupatorin has been reported to date. In the present study, ultra-high-performance liquid chromatography coupled with hybrid triple quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) combined with an efficient online data acquisition and a multiple data processing method were developed for metabolite identification in vivo (rat plasma, bile, urine and feces) and in vitro (rat liver microsomes and intestinal flora). A total of 51 metabolites in vivo, 60 metabolites in vitro were structurally characterized. The loss of CH2, CH2O, O, CO, oxidation, methylation, glucuronidation, sulfate conjugation, N-acetylation, hydrogenation, ketone formation, glycine conjugation, glutamine conjugation and glucose conjugation were the main metabolic pathways of eupatorin. This was the first identification of metabolites of eupatorin in vivo and in vitro and it will provide reference and valuable evidence for further development of new pharmaceuticals and pharmacological mechanisms.

Eupatorin (855-96-9, purity > 98.94%) was purchased from Chengdu Desite Biological Technology Co., Ltd. (Chengdu, China)

上一篇：The Journal of Supercritical Fluids-26 August 2019 藤黃酸

下一篇：Sustainable Chemistry and Pharmacy-26 March 2020 補骨脂素補骨脂苷

Afrormosine CAS:550-79-8 中藥對照品標準品

產品編碼：DA0040產品名稱：Afrormosine英文名:AfrormosineCAS登錄...

人妻少妇免费午夜无码区,久久爆乳AⅤ无码一区二区,日本精品久久久久影院日本,99精品66AV99精品